Area of Research

• Our lab studies the interactions of skeletal and hematopoietic cellular lineages in postnatal bones of mice and humans using a stem cell-centric approach. Interrogating skeletal stem cell biology during development, homeostasis and under pathological conditions, e.g., aging and cancer/disease, allows us to dissect the cellular niches and molecular signals maintaining skeletal as well as hematopoietic cell output. Our long-term goal is to leverage our discoveries to develop strategies to prevent and target skeletal stem cell-based bone and hematopoietic pathologies.